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| Lindsay Lohan | Cady Heron | |
| Rachel McAdams | Regina George | |
| Tina Fey | Ms. Norbury | |
| Ana Gasteyer | Betsy Heron | |
| Lizzy Caplan | Janis Ian | |
| Lacey Chabert | Gretchen Wieners | |
| Tim Meadows | Mr. Duvall | |
| Amy Poehler | Mrs. George | |
| Amanda Seyfried | Karen Smith | |
| Daniel Franzese | Damian | |
| Jonathan Bennett | Aaron Samuels |
| Director |
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| Producer | Lorne Michaels
Jennifer Guinier |
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| Writer/Composer | Rosalind Wiseman
Tina Fey |
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| Cinematography | Daryn Okada
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Raised in African bush country by her zoologist parents, Cady Heron thinks she knows about survival of the fittest. But the law of the jungle takes on a whole new meaning when the home-schooled 15-year-old enters public high school for the first time and encounters psychological warfare and unwritten social rules that teenage girls face today. |
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