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| Ian McKellen | Sherlock Holmes | |
| John Sessions | Mycroft Holmes | |
| Philip Davis | Inspector Gilbert | |
| Hiroyuki Sanada | Tamiki Umezaki | |
| Michael Culkin | Bank Manager | |
| Laura Linney | Mrs. Munro | |
| Nicholas Rowe | Matinee 'Sherlock' | |
| Patrick Kennedy | Thomas Kelmot | |
| Roger Allam | Dr. Barrie | |
| David Foxxe | Chemist | |
| Frances de la Tour | Madame Schirmer | |
| Hattie Morahan | Ann Kelmot | |
| Mike Burnside | Ann's Solicitor | |
| Takako Akashi | Maya Umezaki | |
| Milo Parker | Roger | |
| Zak Shukor | Masuo Umezaki | |
| Charles Maddox | Oswald | |
| Oliver Devoti | Ticket Agent | |
| Phil Davis | Inspector Gilbert | |
| Nicholas Rowe | Matinee 'Sherlock Holmes' | |
| Sam Coulson | Matinee 'Thomas Kelmot' | |
| Frances Barber | Matinee 'Madame Schirmer' | |
| Hermione Corfield | Matinee 'Ann Kelmot' | |
| Kit Connor | Boy | |
| Zoe Rainey | Boy's Mother | |
| Eileen Davies | Lady on Platform | |
| Colin Starkey | Dr. John Watson |
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| Producer |
Anne Carey
Emile Sherman Anne-Marie Casey Len Blavatnik Luca Borghese |
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| Writer/Composer |
Bill Condon
Jeffrey Hatcher Mitch Cullin Arthur Conan Doyle |
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| Cinematography |
Tobias A. Schliessler
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| Music |
Carter Burwell
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The story is set in 1947, following a long-retired Holmes living in a Sussex village with his housekeeper and rising detective son. But then he finds himself haunted by an unsolved 50-year old case. Holmes' memory isn't what it used to be, so he only remembers fragments of the case: a confrontation with an angry husband, a secret bond with his beautiful but unstable wife. |
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