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| Queen Latifah | Ana | |
| Vianca Mercedes | Drug addict | |
| Anna Deavere Smith | Lucille | |
| Wendell Pierce | Slick | |
| Rachel Nicks | Kelly | |
| Evan Ross | Amare | |
| Gloria Reuben | Sandra | |
| Tony Rock | Ness | |
| Darrin Dewitt Henson | MJ2 | |
| Tracee Ellis Ross | Tanya | |
| Limary Agosto | Woman #1 | |
| Carlo Alban | Andre | |
| Sidné Anderson | Sister Bernice | |
| Dorothea Golden | Peer Counselor #1 | |
| Chyna Layne | Deyah | |
| Angel Magee | Peer Counselor #2 | |
| Carol Magee | Peer Counselor #3 | |
| Ivone Negron | Peer Counselor #4 | |
| Rayelle Parker | Kim | |
| Lorraine Platt | Peer Counselor #5 | |
| Cedric Sanders | Simon | |
| Brandon O'Neil Scott | Markus | |
| Heather Simms | Woman #2 | |
| Myra Lucretia Taylor | Dr. Cooper | |
| Willie E. Teacher | Jean Claude | |
| Andrea Williams | Herself | |
| Charisse Woodall | Young Woman | |
| Eric Arriola | Student/Busboy | |
| Annie Basulto | Basketball player | |
| Brandon Scott | Markus |
| Director/Choreographer |
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| Producer |
Otis Best
Mark A. Baker |
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| Writer/Composer |
Nelson George
Jim McKay Hannah Weyer |
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| Cinematography |
Uta Briesewitz
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| Music | Stuart Matthewman
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The true-life story of a mother who overcame an addiction to crack and became a positive role model and an AIDS activist in the black community. |
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