A young man named Eric visits the private gay sex club known as The Lair. He meets Colin, the club manager. They have sex in a back room and Colin, revealing himself to be a vampire, attacks and kills Eric. Damian, the leader of the vampire group, orders Frankie, the club's janitor and familiar (wannabe-vampire) to dispose of Eric's body. The next day, Sheriff Trout finds the body, the latest in a string of "John Doe murders." Reporter Thom meets Frankie, who gives him a necklace Eric had worn. Fellow reporter Laura recognizes the necklace as an amulet from a book detailing myths and legends of the Coast. Laura's boyfriend, Jimmy, resents her taking time with work then with him. Later at home, Thom's jealous boyfriend Jonathan confronts him, then takes the necklace and goes to The Lair in search of Frankie.

Jonathan survives the attack and is taken to the hospital, catatonic. Meanwhile, Thom and Laura research the history of the Coast further and discuss the possibility of vampires being responsible for the John Doe attacks. At the Lair, Damian works on a portrait of himself which, similar to 'The Picture of Dorian Gray', he says holds his curse. He and Colin agree to finish off Jonathan.

Damian introduces the newly-risen vampire Eric to the rest of the Lair's "inner circle." Thom tracks Frankie to the club seeking answers about the attack on Jonathan but a terrified Frankie refuses to help. Damien spies Thom's card and telepathically links to him, ordering him to hang himself. Laura intercedes just in time to save Thom. Meanwhile, Damian goes to Jonathan's hospital room to kill him but is interrupted by Thom and Laura. Dr. Belmont and Sheriff Trout, having discovered a stamp on Eric's hand in ultraviolet ink, are startled to discover the same stamp on Jonathan and Thom's hands.

A shaken Damian confides in Colin that Thom is a double of Richard DeVere, the vampire who painted the portrait and who transformed Damian. Damian had driven a stake through DeVere's heart and stolen the painting, which now bore the evidence of his evil deed on its face. Meanwhile, Dr. Belmont injects Jonathan with an experimental drug which revives him, but Jonathan is stricken with amnesia. Back at The Lair, Damian mentally entrances Thom and commands him to his side. Also, Colin enlists Frankie in a plot against Damian. Damian, wavering in his belief that Thom is DeVere reincarnated, takes Thom to see the portrait, only to discover it missing.

As Damian worries, the sheriff arrives at the club and momentarily spots Eric. Sheriff Trout warns Damian that he'll be watching him. The doctors see that Jonathan's neck wound is almost completely healed and they discharge him to Laura. Laura, sporting a black eye from her abusive boyfriend Jimmy, takes him home. Meanwhile, Damian gathers the family together and accuses one of them of betrayal, demanding the return of the portrait. Privately, Colin sows seeds of doubt about Eric in Damian's mind. Damian takes Thom to the cell and locks him in, then kills Eric by driving a wooden spear through his heart. Eric's body is disposed of and when it's found again, a perplexed Sheriff Trout starts to work on getting a search warrant for The Lair. Back at Thom and Jonathan's place, Colin mystically entrances Laura and sets her off to kill Jonathan. Jonathan dodges the strike. As Laura pursues him, Jimmy enters looking for her and she stabs and kills Jimmy by accident.

Frankie lures Damian to a store room saying the portrait is there. Colin attacks Damian and seals him behind a brick wall. Colin goes to Thom in his cell and tells him he has twelve hours to live. With Laura in jail for Jimmy's murder, Sheriff Trout obtains his warrant and he, Jonathan and Deputy Rogers go to search The Lair. At the same time, Thom concludes his recording and moments later his cell door mysteriously unlocks. He escapes, but not before encountering a vampire. Thom pulls off the vampire's amulet and the vampire disintegrates. Safely back home, Thom calls Dr. Belmont and learns of Laura's arrest. At The Lair, Sheriff Trout, Jonathan and Rogers split up. Rogers discovers several sleeping vampires, who awaken and attack him. At the jail, Laura tells Thom that Jonathan has gone to The Lair. Thom races over. Colin encounters Jonathan and moments later Trout confronts Colin. Frankie appears and opens fire on the sheriff, who returns fire. Frankie is killed and Trout is gravely wounded. Jonathan grabs a gun and fires on Colin, who, unaffected, vanishes. Thom arrives and spies Trout on the floor. As he tries to help him, Jonathan finally reveals himself as a vampire and attacks Thom.