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| Maya Rudolph | Diane Birch | |
| Fred Armisen | Elliot Birch | |
| June Diane Raphael | Devin | |
| Nick Kroll | Nick Birch / Hormone Monster / Coach Steve | |
| Jenny Slate | Missy | |
| Jason Mantzoukas | Jay Bilzerian | |
| Jordan Peele | Ghost of Duke Ellington | |
| Jessi Klein | Jessi Glaser | |
| John Mulaney | Andrew Glouberman | |
| Andy Rannells | Matthew | |
| Paula Pell | Barbara Glouberman | |
| Joe Wengert | ||
| Richard Kind | Marty Glouberman | |
| Jessica Chaffin | Shannon Glaser | |
| Seth Morris | Greg | |
| Neil Casey | ||
| Kat Dennings | Leah Birch | |
| Jon Daly | Judd Birch | |
| Chelsea Peretti | Monica | |
| Jak Knight | DeVon | |
| Kristen Bell | Uninterested Girl | |
| Heather Lawless | Jenna Bilzerian | |
| Rob Huebel | Mr. Lizer | |
| Jack McBrayer | Pubic Hair #1 | |
| Paul Scheer | Kurt Bilzerian | |
| Nick Kroll | Nick Birch | |
| Jenny Slate | Missy Foreman-Greenwald | |
| Joe Wengert | Teacher | |
| Seth Morris | Ninth Grader | |
| Neil Casey | Lars | |
| Chelsea Peretti | Monica Foreman-Greenwald | |
| June Diane Raphael | Devin LeSeven | |
| Andy Rannells | Matthew MacDell |
| Director/Choreographer |
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| Producer |
Jennifer Flackett
Mark Levin Blair Fetter Joe Wengert |
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| Writer/Composer |
Jennifer Flackett
Mark Levin Andrew Goldberg Peter Knight Emily Altman Nick Kroll |
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| Music |
Mark Rivers
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Teenage friends find their lives upended by the wonders and horrors of puberty. |
| 26 mins 9/29/2017 1. Ejaculation | ||
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As Andrew falls under the spell of the randy Hormone Monster, his buddy Nick becomes obsessed with the lack of changes in his own body.
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| 25 mins 9/29/2017 2. Everybody Bleeds | ||
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A field trip goes from awkward to mortifying as Jessi navigates the demands of coupledom and gets her first period -- inside the Statue of Liberty.
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| 27 mins 9/29/2017 3. Am I Gay? | ||
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A trailer for a new movie starring The Rock leaves Andrew questioning his sexuality. Jessi and Nick's budding romance turns ugly fast.
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| 27 mins 9/29/2017 4. Sleepover: A Harrowing Ordeal of Emotional Brutality | ||
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While the boys head to Jay's for a testosterone-fueled sleepover, Jessi throws a party of her own and gets caught up in mean-girl drama.
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| 27 mins 9/29/2017 5. Girls Are Horny Too | ||
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A steamy novel making the rounds at school inspires Jessi to explore her own sexuality -- and leaves the boys totally confused about what girls want.
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| 27 mins 9/29/2017 6. Pillow Talk | ||
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Nick drags Andrew into the city to visit an old camp crush, but the day doesn't go as planned. Jay embarks on an emotional journey with his pillow.
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| 27 mins 9/29/2017 7. Requiem for a Wet Dream | ||
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Andrew struggles to keep the Hormone Monster in check as he works with Missy on a science fair project. Jessi and Matthew have fun at Jay's expense.
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| 26 mins 9/29/2017 8. The Head Push | ||
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When Leah hosts a party for the high school drama crowd, Nick wrestles with a romantic dilemma, and Andrew and Missy witness a disturbing scene.
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| 26 mins 9/29/2017 9. I Survived Jessi's Bat Mitzvah | ||
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Family blowups, secret liaisons and an unflattering dress make Jessi's bat mitzvah a night to remember.
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| 27 mins 9/29/2017 10. The Pornscape | ||
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Andrew tries to drown his sorrows in a sea of porn, only to become hopelessly addicted. Coach Steve becomes a suspect in a murder spree.
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